steveroyle

steveroyle, 10 days ago to random

The Lysosomes and Endocytosis GRC looks great this year. Sadly I'm not going 🙁

#CellBiology #MembraneTrafficking

https://www.grc.org/lysosomes-and-endocytosis-conference/2024/

steveroyle, 14 days ago to random

This is terrible news about Andrew Fry. He was a rigorous scientist and a very generous person. We collaborated on a fantastic paper led by Laura O’Regan in his lab on Hsp72. Although this is the only paper we're co-authors on, we had many joint meetings and discussions with his group and the Bayliss lab.

steveroyle, 15 days ago to accessibility

How can we improve #accessibility for scientific conferences? This short guide by Ulla McClurg covers many of the issues that organisers (and attendees) can consider.

#academia #disability

https://journals.biologists.com/jcs/article/137/10/jcs261858/352179/A-short-guide-to-addressing-accessibility-at

steveroyle, 23 days ago to random

What's the rule? Three crashes of Word and it's time to go home? I'm on two.

#LifeOfPI

steveroyle, 27 days ago to random

Interesting read on "Finding my leadership style" by Helen Walden. A personal reflection on being a PI, a Head of School with a side order of doing so as a woman.

Sorry, it's paywalled (and I have to say very difficult to access even with a subscription) but I enjoyed reading it.

#LabLife #LifeOfPI

https://doi.org/10.1016/j.chembiol.2024.04.010

steveroyle, 29 days ago to random

Google offers “web search” option without all the AI gunk. Idea: they could maybe make this default?

#TurnBackTheClock

https://www.theverge.com/2024/5/14/24074314/google-now-offers-web-search

steveroyle, 1 month ago to random

It seems I have found a new way to procrastinate on a grant application. Using #Rstats to make my Gantt chart!

steveroyle, 1 month ago to random

This is cool. Wade Harper’s lab are experimenting with publishing direct to their lab website.
https://harperlab.pubpub.org

There is one pub up at the moment which is also on bioRxiv
https://harperlab.pubpub.org/pub/nlrp3/release/1

An editor has been assigned and it looks like peer review will be totally open.

The first author Robert Hollingsworth has written a thread on the bad place about his motivations behind this expt (seek it out if you're interested!)

steveroyle, 2 months ago to random

This preprint on native synaptic vesicles structure comes hot on the heals of related work from others.

The images are so cool. Clathrin coated vesicles in synapses are only partially coated.

http://biorxiv.org/cgi/content/short/2024.04.11.588828v1

#cellbiology

steveroyle, 2 months ago to Espresso

Having just serviced and replaced seals on a La Pavoni #espresso machine using nothing but #cycling tools and bike grease, I am wondering if I now qualify for Italian citizenship.

steveroyle, 2 months ago to microscopy

Preprint describing Nellie, a napari plugin for automated organelle segmentation. Results look impressive!

https://arxiv.org/abs/2403.13214

repo (with video): https://github.com/aelefebv/nellie

#CellBiology #microscopy #napari

steveroyle, 2 months ago to random

My calendar for tomorrow shows a quadruple booking. Only a triple booking today.

#LifeOfPI

steveroyle, 2 months ago to random

Wow, this looks exciting!

“Atomically accurate de novo design of single-domain antibodies”

from the Baker lab (of course)

https://www.biorxiv.org/content/10.1101/2024.03.14.585103v1

#RFdiffusion #proteinDesign #cellBiology

steveroyle, 2 months ago to random

Post by Markus Meister about @eLife ’s publishing model. Positive assessment and a plea to make “live” preprints & abandon typesetting.

https://markusmeister.com/2024/03/17/a-year-into-elifes-new-publishing-model/

#scientificpublishing

steveroyle, 3 months ago to random

What fraction of a journal's papers are preprinted?

tl;dr: in cell/dev biol journals it's about 25-50%

https://quantixed.org/2024/03/09/pre-self-what-fraction-of-a-journals-papers-are-preprinted/

steveroyle, 3 months ago to random

This is a cool preprint. Neuroscience aside, for a cell biologist, the idea that sleep-deprivation can alter mitochondria morphology and mitochondria-ER contact sites to replenish lipids, is very exciting.

“Mitochondrial origins of the pressure to sleep”

https://www.biorxiv.org/content/10.1101/2024.02.23.581770v1

steveroyle, 3 months ago to random

I have 38 papers in my “papers to read” pile. Seriously tempted to delete the list and start over. I think it’s the only route to zero.

steveroyle, 4 months ago to random

Awful news. Kelvin Kiptum - current marathon world record holder - has died aged only 24.
https://www.theguardian.com/sport/2024/feb/11/marathon-world-record-holder-kelvin-kiptum-dies

steveroyle, 4 months ago to random

Oh ImageJ, why are you so slow…

If this takes much longer I will post about another exciting paper.

steveroyle, 4 months ago to random

Seen on the other place.

I have been mystified why K represented Lysine for many years. Undergrad #biochemistry lecturer said “I don't know why, but I assume it is because of the end of the side chain looks like a K”. Well, turns out the answer is more simple.

Source: M Eugenio Vazquez. Posted in honour of Margaret Dayhoff, inventor of the single-letter amino acid code

steveroyle, 4 months ago to Mac

Happy fake 40th birthday to my fellow #Mac nerds who put 24th Jan 1984 as their date of birth when signing up for random things.

steveroyle, 4 months ago to random

I'm all for bees in #StructuralBiology papers.

Source: https://www.biorxiv.org/content/10.1101/2024.01.21.576499v1

steveroyle, 5 months ago to random

Addgene is stopping all activity on Twitter/X

https://blog.addgene.org/addgene-is-stopping-use-of-x

steveroyle, 5 months ago to random

In December I asked for suggestions of papers for a course I teach. Thank you to those who responded.

Here is the full list for anyone interested. It's a selection of twenty or so cool papers in biology from last year. I'll find out this afternoon which one(s) the students have picked for their coursework!

https://quantixed.org/2024/01/08/papers-for-md9a8-2024-edition/

steveroyle, 5 months ago to random

“This also explains our publisher's strapline ‘Supporting biologists, inspiring biology’, which is in sharp contrast to the aims of profit-fuelled publishers, ‘Exploiting biologists, constraining biology’.”

Seema and Michael telling it like it is!

@J_Cell_Sci and @Co_Biologists Rock!

https://journals.biologists.com/jcs/article/136/24/jcs261856/339107/Journal-of-Cell-Science-more-than-just-a-journal