#IDMastodon#COVIDisAirborne#opthalmology. #SARSCoV2 uses ACE2 to enter host cells in various organs, including ocular structures.Different forms of ocular involvement have been reported including #conjunctivitis ,#episcleritis & acute corneal graft rejection . Ocular manifestations may occur before, during, or after systemic infection, & there is no evidence that ocular involvement is related to the severity of the systemic disease .
Back in 2013 I developed an outreach program to address #misinformation about infectious diseases, prevention and #vaccines. It combined history, theatre and science. I took it to over a dozen street festivals. Local medical, bioscience, public health students and the odd doctor and public health professional put on historic costumes, and were each given an historic story based on the pre-vaccine era they time-traveled from. The histories gave the passersby we talked to an idea of what life was like pre-vaccines. The fact these costumed people were experts meant visitors could have really informed conversations. Each festival day, we talked to 300-500 individuals. Then COVID happened.
While we faced the odd angry antivaxxer pre-pandemic, I fear that if we were to do these events now there could be more serious trouble.
It was also difficult getting public funding for it as I refused any support from pharmaceutical companies -- and there are costs with putting this sort of event on.
I'm not sure what I can do with this program in future, but I haven't forgotten about it.
Music to my ears: "We need multipronged and imaginative basic scientific and epidemiological research to expand our understanding of what we can do to prevent or mitigate the next influenza pandemic."
Many potential pathways to future pandemic #influenza
"...researchers thought that chain-terminating antiviral drugs were strictly a product of human ingenuity, developed from advances in scientific understanding of viral replication. However, the discovery that a protein in your cells named viperin synthesizes a natural chain-terminating antiviral has revealed a new side of your immune system."
Your immune system makes its own antiviral drug—and it’s likely one of the most ancient
#IDMastodon#CovidIsNotOver#Reproductivemedicine#LongCovid causative’s sexual dysfunction had been most underreported issues. The neuropsychiatric sx, sleep disturbances, sexual dysfunction in LC can help in building better follow-up strategies for #COVID19 .Among #PostCOVID Survivors unusual sx of excessive exhaustion, dyspnea, brain fog, anxiety, & mood disturbances can linger for months to years. Some other symptoms of LC may include sexual dysfunction, headaches & sleep disturbances
"A major barrier for testing alternative antibiotics for #syphilis was the inability to culture the causative agent of the disease [however] it is now possible to test T pallidum susceptibility to antimicrobial agents to determine the [MICs] associated with each compound."
Antimicrobial susceptibility of #Treponema pallidum subspecies pallidum: an in-vitro study
> Both SARS-CoV-2 and non-COVID-19 acute respiratory infections are associated with a wide range of symptoms more than 4 weeks after the acute infection<
In other words, long Covid is a thing, but is not completely unique to Covid.
"Long-term symptom profiles after COVID-19 vs other acute respiratory infections: an analysis of data from the COVIDENCE UK study"
#IDMastodon#priondisease After #COVID19 A #CaseReport
A few cases of PrD after #COVID19 with various neurological complications have been recognized in people after contracting #COVID19. While anosmia is considered a regular consequence of COVID, it is typically underrecognized as cranial nerve I dysfunction, a common neurological complication.
#IDMastodon#Viralimmunology@Nature
Overview & Summaries the role of cell death in #SARSCoV2 infection & #DrugDevelopment in light of #COVID19. #CellDeath mechanisms have a vital role in maintaining a suitable environment to achieve normal cell functionality. Nonetheless, these processes are dysregulated, potentially contributing to disease pathogenesis.
#IDMastodon#CovidIsNotOver@cidrap@cdcgov today noted that #COVID19 hospitalizations are up 8.7% and deaths up 4.5% in the most recent reporting week, though numbers are still quite low. Roughly 18,900 Americans were hospitalized for the virus in the first week of Sept.
Omicron lineage EG.5 represented 24.5% of cases in 🇺🇸 , FL.1.5.1 represented 13.1% of cases. Variants XBB.1.16 & XBB.1.16.6 accounted for 10% each of all cases tracked in the first 2 weeks of Sept.