Clever neuronal activity labelling strategy: Engineered Ca2+ sensor biotinylates nearby proteins. Those proteins can then be stained - works for single vesicles, organelles, dendritic compartments, all the way to neuronal engrams. Both in culture and in vivo!
"A petavoxel fragment of human cerebral cortex reconstructed at nanoscale resolution" by Shapson-Coe et al. 2024 (Lichtman lab).
The reconstruction at its current state is already useful and very interesting. Here is to hoping the authors will put in more time and resources to further polish it.
A remarkable finding from Shapson-Coe et al. 2024 paper on human brain #connectomics: the presence of canalized connections in the human brain cortex. Canalized in the Kauffman boolean networks sense [1], which here means: among the many synaptic inputs that any one neuron integrates, some are far stronger (by number of synapses) than the rest.
[1] Canalisation as a term was introduced by Waddington in 1942 in the context of genetics to mean "some phenotypic traits are very robust to small perturbations" https://en.wikipedia.org/wiki/Canalisation_(genetics)
“Collaborative hunting in artificial agents with deep reinforcement learning” by Tsutsui et al. 2024.
“using computational multi-agent simulations based on deep reinforcement learning, we demonstrate that decisions underlying collaborative hunts do not necessarily rely on sophisticated cognitive processes.”
“This has implications for a reassessment, and perhaps a widening, of what groups of animals are believed to manifest cooperative hunting.”
This summer there will be four courses 😯:
Computational Neuroscience, NeuroAI, Deep Learning, and Computational Tools for Climate.
Mentors will hold a one-hour meeting every week with a small cohort of students, where they will discuss with them and help them progress in their journey in industry and academia.
Depuis l'invention du #cinéma, les grands réalisateurs savent captiver et émouvoir le public en manipulant les images et les sons. Des chercheurs en #neuroscience ont voulu comprendre ce qui se passe dans le cerveau lorsqu’on regarde un film, un domaine d’études appelé le #neurocinéma. Ces découvertes #scientifiques sont maintenant reprises par des cinéastes afin de réaliser des films encore plus puissants qu’avant.
Seeing the Mind: Spectacular Images from Neuroscience, and What They Reveal about Our Neuronal Selves by Stanislas Dehaene, 2023
A lavishly illustrated and accessibly explained deep dive into the major new findings from cognitive neuroscience.
Who are we? To this age-old question, contemporary neuroscience gives a simple answer: we are exquisite neuronal machines.
"Schreckstoff: It takes two to panic", a dispatch by @MarcusStensmyr 2024
"Schreckstoff (fear substance) is an alarm signal released by injured fish that induces a fear response. Its chemical nature has long been debated. A new study finds that zebrafish Schreckstoff is composed of at least three components, two of which elicit the fear response only in combination."
Happy birthday to #neurologist Santiago Ramón y Cajal (1852 - 1934), here in front of Purkinje and granule cells from a pigeon, based on one of his own drawings! Cajal &Golgi won the Nobel in 1906, "in recognition of their work on the structure of the nervous system". He was as much of an artist as he was a scientist & his 100s of drawings are still used for teaching purposes.
🧵1/n
#sciart#linocut#printmaking#histstm#PurkinjeCell#neuroscience#MastoArt