@steveroyle@biologists.social
@steveroyle@biologists.social avatar

steveroyle

@steveroyle@biologists.social

I'm into chord changes and cell biology.

Professor at University of Warwick. Director, Trustee and Deputy Chair of The Company of Biologists. Affiliate of bioRxiv. Author of "The Digital Cell". Views my own, obviously.

#CellBiology #MembraneTrafficking #CellDivision #Microscopy #ImageAnalysis #Science #ScienceMastodon #Academia #AcademicMastodon and #Music #Running #Cycling

This profile is from a federated server and may be incomplete. Browse more on the original instance.

steveroyle, to random
@steveroyle@biologists.social avatar

Wow, this looks exciting!

“Atomically accurate de novo design of single-domain antibodies”

from the Baker lab (of course)

https://www.biorxiv.org/content/10.1101/2024.03.14.585103v1

#RFdiffusion #proteinDesign #cellBiology

steveroyle, to random
@steveroyle@biologists.social avatar

My calendar for tomorrow shows a quadruple booking. Only a triple booking today.

steveroyle,
@steveroyle@biologists.social avatar

That was not meant to be a "look at me” post, btw. Just highlighting how bananas the workload of this job can be sometimes. #LifeOfPI

steveroyle, to random
@steveroyle@biologists.social avatar

Post by Markus Meister about @eLife ’s publishing model. Positive assessment and a plea to make “live” preprints & abandon typesetting.

https://markusmeister.com/2024/03/17/a-year-into-elifes-new-publishing-model/

steveroyle, to random
@steveroyle@biologists.social avatar

The neuroscientist formerly known as Prince’s audio engineer

https://www.nature.com/articles/d41586-024-00791-5

steveroyle, to random
@steveroyle@biologists.social avatar

What fraction of a journal's papers are preprinted?

tl;dr: in cell/dev biol journals it's about 25-50%

https://quantixed.org/2024/03/09/pre-self-what-fraction-of-a-journals-papers-are-preprinted/

steveroyle, to random
@steveroyle@biologists.social avatar

Surely this is a resigning matter? UK's “science minister" libelled two academics (by uncritically repeating a false claim by right wing think tank Policy Exchange) and has to pay damages. It transpires she has done so using the public purse.

https://www.theguardian.com/politics/2024/mar/05/uk-science-minister-michelle-donelan-apologises-and-pays-damages-after-academics-libel-action

steveroyle, to random
@steveroyle@biologists.social avatar

This is a cool preprint. Neuroscience aside, for a cell biologist, the idea that sleep-deprivation can alter mitochondria morphology and mitochondria-ER contact sites to replenish lipids, is very exciting.

“Mitochondrial origins of the pressure to sleep”

https://www.biorxiv.org/content/10.1101/2024.02.23.581770v1

steveroyle, to random
@steveroyle@biologists.social avatar

I have 38 papers in my “papers to read” pile. Seriously tempted to delete the list and start over. I think it’s the only route to zero.

andrewplested, to random

Greetings from the Space Science Journal.

I recently came across your article titled "Measurements of the timescale and conformational space of AMPA receptor desensitization".

I am writing to extend an invitation for you to submit your paper for publication in our journal.

#ReceptorsInSpace #AcademicSpam

steveroyle,
@steveroyle@biologists.social avatar

@albertcardona @andrewplested the existence of #AcademicSpam tells us that there are some who fall for it. This piece changed my mindset:

https://www.nature.com/articles/d41586-023-02553-1

steveroyle, to random
@steveroyle@biologists.social avatar

Awful news. Kelvin Kiptum - current marathon world record holder - has died aged only 24.
https://www.theguardian.com/sport/2024/feb/11/marathon-world-record-holder-kelvin-kiptum-dies

steveroyle, to random
@steveroyle@biologists.social avatar

Oh ImageJ, why are you so slow…

If this takes much longer I will post about another exciting paper.

steveroyle,
@steveroyle@biologists.social avatar

@albertcardona No. How do I do that? Upgrade JDK?

steveroyle,
@steveroyle@biologists.social avatar

@albertcardona thank you!

steveroyle,
@steveroyle@biologists.social avatar

@albertcardona thanks for the offer! Pretty sure the slowness is related to the size of the stacks I am analysing. It's not really a scripting issue, it is single calls that are running slow. Yesterday, generating a 3D distance map for each one was slow. Today, 3D object counter is running slow. It's a memory issue, but as these commands are 3D I don't think I can avoid loading the whole thing in.

steveroyle, to random
@steveroyle@biologists.social avatar

Seen on the other place.

I have been mystified why K represented Lysine for many years. Undergrad #biochemistry lecturer said “I don't know why, but I assume it is because of the end of the side chain looks like a K”. Well, turns out the answer is more simple.

Source: M Eugenio Vazquez. Posted in honour of Margaret Dayhoff, inventor of the single-letter amino acid code

elduvelle, (edited ) to academia
@elduvelle@neuromatch.social avatar

People who write : do you write about

  1. projects that you’ve already almost completed (hiding the fact that they’re almost completed, so that you can use the funding for completely new projects), or
  2. new projects that you haven’t really started yet (for which you might just have some preliminary data)?

Do you think 1) is unethical? Do you think 1) is necessary? Do you think 1) has the highest chances of funding? Please comment :)

steveroyle,
@steveroyle@biologists.social avatar

@elduvelle IMO 1 is unethical. I've heard it's the norm in other places, but here in the UK it's a no-no.

steveroyle,
@steveroyle@biologists.social avatar

@elduvelle ha. I think he's saying two things: hiding completed work is not allowed and that UKRI is risk averse.

steveroyle, to Mac
@steveroyle@biologists.social avatar

Happy fake 40th birthday to my fellow #Mac nerds who put 24th Jan 1984 as their date of birth when signing up for random things.

steveroyle, to random
@steveroyle@biologists.social avatar

I'm all for bees in #StructuralBiology papers.

Source: https://www.biorxiv.org/content/10.1101/2024.01.21.576499v1

roaldarboel, to random

Is it possible to filter out posts from certain accounts in the Home feed while having them in a separate list? Specifically wanting to have posts from journals (e.g. @biorxivpreprint ) in a “Journals” list, but not see their posts in the home feed.

steveroyle,
@steveroyle@biologists.social avatar

@roaldarboel yes. I have exactly this set up. Just follow the bioRxiv bot of your choice. Add it to list and then select “Hide these posts from home". I can do this within Ivory but it works on the web app too.

steveroyle, to random
@steveroyle@biologists.social avatar

Addgene is stopping all activity on Twitter/X

https://blog.addgene.org/addgene-is-stopping-use-of-x

steveroyle,
@steveroyle@biologists.social avatar

I’d like to point out that I didn’t leave the anonymous comment on that page saying that they should join mastodon - although I fully agree!

steveroyle, to random
@steveroyle@biologists.social avatar

In December I asked for suggestions of papers for a course I teach. Thank you to those who responded.

Here is the full list for anyone interested. It's a selection of twenty or so cool papers in biology from last year. I'll find out this afternoon which one(s) the students have picked for their coursework!

https://quantixed.org/2024/01/08/papers-for-md9a8-2024-edition/

albertcardona, to random
@albertcardona@mathstodon.xyz avatar

Our work made it into the "7 medical breakthroughs that gave us hope in 2023" of #NatGeo – proud! They even chose our image of the #Drosophila larval brain neurons for the header:

https://www.nationalgeographic.com/premium/article/medical-breakthroughs-2023-gene-therapy-crispr-cancer-fertility

#connectomics

steveroyle,
@steveroyle@biologists.social avatar

@albertcardona that's very cool - congrats!
And if I can ask a dull question: do you make those images in Blender or do you use a different package?

  • All
  • Subscribed
  • Moderated
  • Favorites
  • •
  • JUstTest
  • everett
  • rosin
  • thenastyranch
  • mdbf
  • osvaldo12
  • Youngstown
  • InstantRegret
  • slotface
  • DreamBathrooms
  • kavyap
  • ngwrru68w68
  • tester
  • normalnudes
  • megavids
  • magazineikmin
  • tacticalgear
  • khanakhh
  • GTA5RPClips
  • ethstaker
  • Durango
  • Leos
  • anitta
  • cubers
  • cisconetworking
  • modclub
  • provamag3
  • lostlight
  • All magazines
    •