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We show that a 5-HT1A-selective 5-MeO-DMT analogue is devoid of hallucinogenic-like effects while retaining anxiolytic-like and antidepressant-like activity in socially defeated animals.
Not sure how to phrase it but I guess making it more therapeutic, and less recreational makes it more likely to be a candidate for passing FDA regs.
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It’s justified by power line maintenance and safety, right? Then the amount should be based on how many miles of power lines are running out to your house. That would make it more expensive to live out in the country, where the largest fire-related expenses already are, and cheaper to live in the city. Or we can keep subsidizing sprawl. We already spend billions protecting a few hundred homes from wildfires. Spend billions on freeway widening too. This is probably small compared to those other things.
It would be considered rape if the alleged rapist was poor, or any race other than white. It would probably not be considered rape if the perpetrator was a white man (especially Christian), or a woman.
Welcome to !crossword! Instead of the daily post focusing solely on the NYT crossword like at /r/crossword, we at Lemmy are open to discussion for all daily crosswords....
No use of your body is a pretty desperate situation. Before the procedure he had to yell for his parents that he wanted to use the computer, they’d come sit him upright and put a joystick in his mouth, leaving him unable to speak. And he was often very uncomfortable in that position, so he couldn’t do it long. Now, he can use the computer fully laying down, without anyone’s help. The next logical step would be to have some robotic helper arms.
Anyway he can’t shoot himself. He can’t hold a gun or anything else. There’s little reason for this to be about Musk at all other than money. This is the culmination of decades of research from many medical professionals. It’s about a lot more than one person.
Nobody is making you get a brain chip. Noland did the research, talked about it with his family, and wanted to proceed in spite of the fully disclosed risks. Bodily autonomy is a fundamental human right - if you want to do something or have something done to your body it’s not the governments place to stop you. Safeguards are necessary, and they do exist. You don’t need laws to make sure everybody has the same risk tolerance as you. I can’t fully imagine what it would be like to have no use of my body and no hope of recovery. But I wouldn’t want people like you or me who aren’t in my shoes deciding what I can and can’t do. Honestly if he wanted to have a lethal injection, I believe he should be allowed to make that decision, but he can’t. I’m happy he was able to make some kind of decision, and regain some autonomy, if only temporarily, and not just be a vegetable head in a bed for the rest of his life.
Are you suggesting that the FDA gave Neuralink special treatment in the approval process? Or are you suggesting that the government should specifically shut down anything Musk tries to do, like SpaceX?
I don’t think it’s obvious at all. This is a sample size of one, and it is still working after 3 months.
Globally, a staggering 310 million major surgeries are performed each year; around 40 to 50 million in USA and 20 million in Europe. It is estimated that 1–4% of these patients will die, up to 15% will have serious postoperative morbidity, and 5–15% will be readmitted within 30 days. An annual global mortality of around 8 million patients places major surgery comparable with the leading causes of death from cardiovascular disease and stroke, cancer and injury. If surgical complications were classified as a pandemic, like HIV/AIDS or coronavirus (COVID-19), developed countries would work together and devise an immediate action plan and allocate resources to address it.
My takeaway from that article is mostly that primate research is a big emotional topic for some people, and maybe tech writers shouldn’t write about medical research. Do you think it would be so interesting if it was done on mice? The primate research center in Davis has been there since 1962, and it’s always been controversial. Do you think they’ve just been twiddling their thumbs for 55 years waiting for Neuralink to come along? No, that shit is routine for them. They keep doing it because primate research is still an important step before human trials.
There is no need to ethically green light a medical procedure that is voluntary, of sound mind, and of one’s own will. It’s not your body. It’s not your life. People implant beads and magnets into their bodies and tattoo their faces. People hang themselves from meat hooks for fun. People get circumcised, and pierced. It’s all none of your business.
I agree this is the kind of thing I should find on YouTube, not in an academic journal. But the paper does go into a lot of detail about extraction efficiency, so I guess there might be some useful measurements.
I am curious about the taste. It should be somewhere in between cold brew and hot, but probably closer to cold. Cavitation is a violent process. On a micro scale it’s literally boiling. Then the steam bubble collapses and is instantly cooled because of an almost infinitely big heat sink. So when cavitation occurs near the coffee grounds, some of the extraction would be at much warmer temperatures, for a brief instant.
Yeah, they didn’t even invent it. One company basically tried to do the same brewing technique commercially, but I guess they didn’t get the word out in time: engadget.com/osma-pro-cold-brew-coffee-machine-re…
🤷♂️ Tomato / Potato. Cavitation occurs (the bubble formation) at a temperature below 100C, yes. As the steam bubble shrinks, very high temperatures are reached (super-heated steam). All of that energy, plus the latent heat of condensation is released back into the fluid. At that instant, there is a very small yet-to-be-mixed portion of liquid that may be near the boiling point. That small portion of fluid may undergo a warm-brew process as it cools and mixes. I’m kind of conceptualizing this brewing process like: what if you could heat, mix, and cool the coffee all at once everywhere. But I’ve never observed cavitation and bubble collapse with an ultra high-speed microscope camera, so my concept may be off a bit. I have seen photos of what it does to hardened steel hydropower turbines.
My next question would be, what if you start with ice water? That may give you something like true cold-brew. Another factor to consider is that I believe most cold brew is very oxidized. It might be interesting to try ultrasonic degassing for some period of time before the grounds are added, to see how much of the cold brew flavor is just oxidized coffee.
It seems like the only two options to get tabs nowadays are gtabs and songsterr. I prefer songsterr out of the two, but constantly get harassed to buy the premium version and certain important features are paywalled....
An app called Lamucal can make them for you, lyrics and all.
An older app (now defunct), can be found on archive.org, called Riffstation, can do the chords.
Once you have a version of your song you can put it in an app called JustChords. This app will store, display, and transpose your songs. It also has a search feature to pull tabs from other sources.
I constantly see angry mobs of people decrying “woke”, “critical race theory”, ““grooming””, and whatever other nonsense they made up this week. They march around with guns, constantly appending lib as a prefix to any word they can use to denigrate. They actively plot violence and spew hatred in the open....
I hate racists and bigots, but there’s not much to be done about it. Stress and anger will take years off your own life - don’t let them harm you. On the other hand if you can troll them a bit, you may be sending some of them to an early grave, just with words. It’s not hard to do they’re triggered by anything gay, reparations, dominant women, intelligence and education, health foods, immigrants, solar power, and so on. So you don’t really have to send them any hate, you just need to be an example of the world you want to live in and they’ll rage about it.
“We’ve almost got some of their telecommunications cracked; the front end even runs on a laptop!” The Mac that sunk a thousand ships could have been merely clunky product placement, not a bafflingly stupid tech-on-film moment....
Another big plot hole in the Martian, also present in the book, is that messages are encoded in hexadecimal. But then why did he have a separate question mark card, when all punctuation can be encoded in ASCII/hex? Also both him andNASA wrote in all caps. Again they have a full ascii set. Makes no sense.
Ah so it’s a position where they can read his messages. They does make more sense. However all caps still doesn’t. The messages should have used caps to delineate abbreviated words. Like their first message “HOW ALIVE?” Could have been HwAliv? Which of course could be interpreted as “how are you even alive?” Or “how alive are you?”
Crosswords Saturday 05/11/2024 Discussion
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Chemical tweaks to a toad hallucinogen turns it into a potential drug (arstechnica.com)
See also: Family Guy S02E14 Let’s Go to the Hop
Crosswords Friday 05/10/2024 Discussion
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Californians will see lower electricity rates and a new fee that won’t vary with power use (calmatters.org)
Stormy Daniels testimony reveals the triumph of #MeToo (www.salon.com)
Crosswords Thursday 05/09/2024 Discussion
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Neuralink's first in-human brain implant has experienced a problem, company says (www.cnbc.com)
Scientists Use Ultrasound to Make Cold Brew Coffee in 3 Minutes Instead of 24 Hours (www.404media.co)
YouTube accused of censoring Macklemore's "Hind's Hall" (www.newsweek.com)
Pirating guitar and bass tabs?
It seems like the only two options to get tabs nowadays are gtabs and songsterr. I prefer songsterr out of the two, but constantly get harassed to buy the premium version and certain important features are paywalled....
How come liberals dont hate conservatives the way conservatives hate liberals
I constantly see angry mobs of people decrying “woke”, “critical race theory”, ““grooming””, and whatever other nonsense they made up this week. They march around with guns, constantly appending lib as a prefix to any word they can use to denigrate. They actively plot violence and spew hatred in the open....
What plot holes could be adequately explained away with a single shot or line of dialogue?
“We’ve almost got some of their telecommunications cracked; the front end even runs on a laptop!” The Mac that sunk a thousand ships could have been merely clunky product placement, not a bafflingly stupid tech-on-film moment....