📌 Scientists have created a vaccine that has the potential to protect against a broad range of coronaviruses, including varieties that are not yet even known about.
📌 The experimental shot, which has been tested in mice, marks a change in strategy towards “proactive vaccinology”, where vaccines are designed and readied for manufacture before a potentially pandemic virus emerges.
The envelope protein is highly conserved among human #coronaviruses, suggesting it could be a good drug target. This #PLOSBiology study identifies iPep-SARS2-E and shows that it inhibits #SARSCoV2 infection in lung organoids and in mice.
Two #coronaviruses isolated from central nervous system tissue of two #multiplesclerosis patients pubmed.ncbi.nlm.nih.gov/7403860/
Note the year (1980) and follow the related and citing literature. #Textbook ?
For Patient Safety, It Is Not Time to Take Off Masks in Health Care Settings | Annals of Internal Medicine https://www.acpjournals.org/doi/10.7326/M23-1190# “Although gold-standard evidence is not available, we argue that, despite the lack of clinical efficacy trials (as with the widely accepted practice of #HandHygiene), #masking in interactions between # patients and #HealthCare personnel should continue to receive serious consideration as a patient safety measure.”
“Laboratory studies have done what clinical research has not and demonstrated that #SurgicalMasks—and to a greater extent, filtering facepiece #respirators—are effective in limiting the spread of #aerosols and #droplets from individuals infected with #influenza, #coronaviruses, and other #respiratory viruses. Although not 100% effective, they substantially reduce quantities of virus expelled during coughing or talking, thereby mitigating risk.