PLOSBiology, 5 months ago to random The BIN1 gene is a key risk locus for #AlzheimersDisease, but how does it impact #TauPathology? This study shows that during aging, the protease legumain is activated and cleaves BIN1, promoting tau #aggregation & spreading of #pathology #PLOSBiology https://plos.io/3tOPYtE
The BIN1 gene is a key risk locus for #AlzheimersDisease, but how does it impact #TauPathology? This study shows that during aging, the protease legumain is activated and cleaves BIN1, promoting tau #aggregation & spreading of #pathology #PLOSBiology https://plos.io/3tOPYtE