mihair, to science
mihair avatar

Stevia is considered a "natural non-caloric sweetener." Saccharin and sucralose are considered "non-nutritive sweeteners" (few or no calories). Aspartame is a "nutritive sweetener" (adds some calories but far less than sugar).
Aspartame comes with a warning to be used cautiously (or not at all) by people with a rare genetic disease (called phenylketonuria, or PKU) because they have trouble metabolizing it; that's not true for the other sweeteners. And all four vary on their level of sweetness and aftertaste, which is likely why people often prefer one over another.

https://www.health.harvard.edu/blog/sweeteners-time-to-rethink-your-choices-2019022215967

gerryflap,
@gerryflap@feddit.nl avatar

Is this a bug are are you intentionally spamming posts about artificial sweeteners? On Lemmy this is basically flooding my feed, but maybe that’s just an issue between Lemmy and Kbin

mihair, to science
mihair avatar

With a low to no calorie sugar count, artificial sweeteners may seem like a treat for people with diabetes. But recent research indicates that artificial sweeteners may actually be counterintuitive, especially if you’re looking to manage or prevent diabetes.
In fact, the increased consumption of these sugar substitutes may correlate to the increase of obesity and diabetes cases.

https://www.healthline.com/health/type-2-diabetes/diabetes-stevia#overview

mihair, to science
mihair avatar

Stevia is an ideal replacement for traditional sugar, especially if you have diabetes or a carbohydrate-controlled diet. That way, you can enjoy sweet foods without dealing with diabetic complications. Unlike normal sugar made of sucrose, stevia contains stevioside. It is a glycoside compound, not a carbohydrate. Table sugar is absorbed into the bloodstream. As stevioside breaks down, the glucose is absorbed in the colon by bacteria.

https://facty.com/food/nutrition/10-surprising-benefits-and-risks-of-the-alternative-sweetener-stevia/?style=quick&utm_source=adwords&adid=267723668343&ad_group_id=57749014289&utm_medium=c-search&utm_term=stevia&utm_campaign=FH-USA-Search-Health-Benefits-and-Risks-of-Stevia&gclid=EAIaIQobChMI1v_2gJqCgQMV1gQGAB1JAgLjEAAYAyAAEgL1VvD_BwE

mihair, to science
mihair avatar

Pancreatic cancer has an extremely poor prognosis, largely due to a poor record for early detection. Known risk factors for pancreatic cancer include obesity, diet, and diabetes, implicating glucose consumption and regulation as a key player. The role of artificial sweeteners may therefore be pertinent to disease kinetics. The oncogenic impact of artificial sweeteners is a highly controversial area.
https://www.frontiersin.org/articles/10.3389/fonc.2017.00018/full

mihair, to science
mihair avatar

Stevia, a zero-calorie sugar substitute, is recognized as safe by the Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA). In vitro and in vivo studies showed that stevia has antiglycemic action and antioxidant effects in adipose tissue and the vascular wall, reduces blood pressure levels and hepatic steatosis, stabilizes the atherosclerotic plaque, and ameliorates liver and kidney damage. The metabolism of steviol glycosides is dependent upon gut microbiota, which breaks down glycosides into steviol that can be absorbed by the host. In this review, we elucidated the effects of stevia’s consumption on the host’s gut microbiota.
https://www.mdpi.com/2076-2607/10/4/744/htm

TheBest,

I have IBS and sugar makes it act up. I use stevia extract as a substitute in products, and I AM constantly working on improving my gut biome health. This was a dense but good read.

mihair, to science
mihair avatar

To help offset potential stevia induced gut challenges, support your gut flora with fiber and prebiotics like FOS10 (fructo-oligosaccharides). Increase your intake of beneficial bacteria Lactobacillus and Bifidus to aid in a healthier gut microbiome.
Consider foods and nutrients like cruciferous vegetables (Brussels sprouts, cabbage, broccoli, cauliflower, kale), silymarin, dandelion, resveratrol, curcumin, magnesium, zinc, limonene, B vitamins, and omega-3 oils to help your liver’s glucuronidation pathway.

https://www.bbc.com/mundo/noticias/2013/07/130717_salud_nutricion_stevia_finde_gtg

mihair, to science
mihair avatar

Ancestral intake of the raw stevia leaf was extremely limited compared to current exposures of refined stevia found in many manufactured food products. I am a proponent of using foods in their natural, whole form when possible.
Avoid processed refined sugars and foods with added sugars, but rather use raw local honey, blackstrap molasses, real maple syrup, or other natural sugars. Think about it, would your grandmother or great grandmother use something like refined stevia in their made from scratch homemade recipes?

https://medlineplus.gov/spanish/druginfo/natural/682.html

I_Has_A_Hat,

Did a bot break or something? Who tf is this and why is he spamming so many posts about the same topic?

mihair, to science
mihair avatar

Artificial sweeteners or intense sweeteners are sugar substitutes that are used as an alternative to table sugar. They are many times sweeter than natural sugar and as they contain no calories, they may be used to control weight and obesity. Extensive scientific research has demonstrated the safety of the six low-calorie sweeteners currently approved for use in foods in the U.S. and Europe (stevia, acesulfame-K, aspartame, neotame, saccharin and sucralose), if taken in acceptable quantities daily. There is some ongoing debate over whether artificial sweetener usage poses a health threat .This review article aims to cover thehealth benefits, and risks, of consuming artificial sweeteners, and discusses natural sweeteners which can be used as alternatives.

https://pubmed.ncbi.nlm.nih.gov/25842566/

mihair, to science
mihair avatar

Stevia rebaudiana Bertoni is a perennial shrub with zero calorie content that has been increasing in popularity for its potential use as an adjuvant in the treatment of obesity. The level of evidence supporting general benefits to human health is insufficient. We conducted a review of the literature summarizing the current knowledge and role in human disease.
A growing body of evidence indicates that Stevia rebaudiana Bertoni is protective against malignant conversion by inhibition of DNA replication in human cancer cell growth in vitro.

https://pubmed.ncbi.nlm.nih.gov/29995279/

madalinai, to science
madalinai avatar

Some research papers conclude that stevia consumption can cause cancer due to DNA breakage and chromosome mutations. However, none of those studies are based on human subjects.
According to a study published in Oncotarget in 2018, steviol significantly limited the growth of human gastrointestinal cancer cells.

https://www.bekarmic.com/blogs/knowledge-base/stevia-and-cancer-everything-about-stevia

detalferous,

How many DNA breakage studies are done in humans?

madalinai, to science
madalinai avatar

The use of steviol glycosides as non-caloric sweeteners has proven to be beneficial for patients with type 2 diabetes mellitus (T2D), obesity, and metabolic syndrome. However, recent data demonstrate that steviol and stevioside might act as glucocorticoid receptor (GR) agonists and thus correlate with adverse effects on metabolism. Herein, we evaluated the impact of steviol, steviol glycosides, and a Greek-derived stevia extract on a number of key steps of GR signaling cascade in peripheral blood mononuclear cells (PBMCs) and in Jurkat leukemia cells.
https://pubmed.ncbi.nlm.nih.gov/28754349/

madalinai, to science
madalinai avatar

Prostate cancer is the second most harmful disease in men worldwide and the number of cases is increasing. Therefore, new natural agents with anticancer potential should be examined and the response of existing therapeutic drugs must be enhanced. Stevia pilosa and Stevia eupatoria are two species that have been widely used in traditional medicine, but their effectiveness on cancer cells and their interaction with antineoplastic drugs have not been studied. The results indicate that SPME and SEME have an inhibitory effect on the viability and migration of prostate cancer cells and do not interfere with the enzalutamide anticancer effect. The data suggest that Stevia extracts may be a potential source of molecules for cancer treatment.

https://pubmed.ncbi.nlm.nih.gov/32102219/

madalinai, to science
madalinai avatar

Steviol glycosides are currently being used as natural sweeteners by the food industry and Stevia rebaudiana has long been used as a sweet plant in South America for patients suffering from diabetes. In this study, a Stevia rebaudiana ethanolic extract (SREE) was prepared, analysed and tested for antioxidant activity in terms of free radical scavenging properties and antiproliferative effects in cervix (HeLa), pancreatic (MiaPaCa-2) and colonic (HCT116) cancer cells. The antiproliferative mechanism was confirmed by testing the effects on cyclin D1-CDK4.
https://pubmed.ncbi.nlm.nih.gov/27071804/

madalinai, to science
madalinai avatar

Hydroponics offers a viable solution for obtaining plant products that are rich in micronutrients and ultramicronutrients, such as selenium. Selenium plays a crucial role in strengthening the body's immune defense and acts as a potent antioxidant. Low levels of selenium have been associated with an increased risk of heart attacks, strokes, and cancer. Stevia rebaudiana Bertoni (SrB), a relatively new crop in plant cultivation, was the focus of the present study. SrB has numerous medicinal and prophylactic properties, and its leaves are rich in macro- and microelements, vitamins, and diterpene glycosides.

https://pubmed.ncbi.nlm.nih.gov/37522778/

madalinai, to science
madalinai avatar

Stevia is unaffected by stomach acid, pancreatic enzymes and the process of digestion. It travels essentially “untouched” by the digestive process until it reaches the large intestine. There it “reacts” with the gut flora. It is then absorbed in the colon and travels to the liver. It is then bound to glucuronic acid via the glucuronidation pathway and eventually excreted through the urine. The glucuronidation pathway is a major liver pathway that detoxifies drugs, pollutants, estrogen, and steroids, etc.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://www.portalsalud.com/cuales-son-los-peligros-de-la-stevia_13092860/

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