Foreskin Morbidity in Uncircumcised Males
Sneppen and Thorup, Pediatrics 2016
"In our patient population, we found that 7.2% (95% CI 3.4–11.0) were diagnosed with autism spectrum disorder (ASD) as a concomitant disease (Table 3). A recent Danish study calculated the prevalence of ASD in Denmark to be 1.5% among boys."
Association found between ASD and childhood penile surgeries. This is reference 1, next toot has #2.
Ritual circumcision and risk of autism spectrum disorder in 0- to 9-year-old boys: national cohort study in Denmark
Frisch & Simonsen, 2015 J. R. Soc. Med.
"We confirmed our hypothesis that boys who undergo ritual circumcision may run a greater risk of developing ASD. This finding, and the unexpected observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families, need attention"
Two different research groups have now found a relationship between early childhood penile surgeries and autism spectrum disorder. The two different studies had different goals, different recruitment approaches, different study variables, and yet the relationship between ASD and circumcision remains quite striking!
For boys undegoing penile genital cutting before age five, the risk of ASD is even higher.
The association between #circumcision and #ASD was first discovered and reported in
Prenatal and perinatal analgesic exposure and autism: an ecological link
Bauer & Kriebel, 2013. Env. Health
"For studies including boys born after 1995, there was a strong correlation between country-level (n = 9) autism/ASD prevalence in males and a country’s circumcision rate (r = 0.98). A very similar pattern was seen among U.S. states and when comparing the 3 main racial/ethnic groups in the U.S. "
@ttpphd reminds me of an article i read recently about two autistic twins, both were diagnosed but one was a college student & very verbal & the other was much more disabled by it & very minimally verbal. The less verbal twin had also had a heart condition in infancy which required major surgery, which resulted in infection which had to be treated.
It seems like there might be some evidence that early life injuries, trauma, immune problems, etc might make autistic traits more pronounced? 🤔
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