No. There’s a huge difference if a program runs in user space or ring 0. Depending on the security policies and admin rights management on your system, malicious software can’t do anything. If you, the user, blindly click “ok” in Windows UAC prompts or run sudo on Linux without thinking, that’s on you. However, kernel-level anti-cheat software always has access and thus is a much more dangerous and sought-after attack vector.
Hell, if you wanted to make extra sure you could spin up a VM with GPU pass-through and play on there. But this is also not possible with kernel-level anti-cheat software because most detect they’re being run in a VM and refuse to start the game.
That’s only the security side of things. If software has shoddy code it will at worst crash itself if it’s not interacting with drivers too much (like games and graphics drivers - and even then the crashes happen because of bugs in the drivers in the first place). If it’s ring zero it can make your system unstable, crashing your entire system and not just the software itself.
Regarding “games that matter”, define your benchmark.
Are we talking about games that have the absolute top financial success? Sure, it’s all the competitive matchmaking games that rely on a somewhat believable competitive integrity of their games. But then again, most kernel-level anti-cheat systems don’t even prevent cheating. It’s a never-ending cat-and-mouse game at the cost of the customer’s privacy, security and stability of their system. Riot themselves have a recent blog post detailing that 1 in 15 League of Legends games had cheaters/scripters on average. Not only that, their new-ish kernel-level anti-cheat Vanguard - like all others - has been defeated. So they need to update. Change methods. Become more invasive. Just never-ending. And new/changed code always has the potential for new bugs, bringing us full circle to security and stability problems.
Or are we simply talking about games that are fun for the individual? There’s a wealth of Singleplayer/Co-op and/or PvE only games that are successful without any kind of invasive anti-cheat. To name a few (you only wanted one, but I’m in the mood): Cyberpunk 2077, Vampire Survivors (and all its offspring), Factorio, Satisfactory, Borderlands (1, 2, Pre-Sequel, 3, Tiny TIna’s Wonderlands), Skyrim, Fallout (3, 4, New Vegas), Starfield (I agree it was a flop, but it mattered), Baldur’s Gate 3 (which had incredible success).
Do I need to go on? This list isn’t even just a personal preference of mine. A lot of these titles were highly anticipated and are hugely successful.
So yeah, you should be sorry for spouting nonsense.