It's been a while, and the Deno ecosystem has improved a lot. Drizzle looks promising as an ORM layer (better than my hacked-together one), and more Fediverse projects in Deno are popping up (#Fedify looks really cool!). But I'm rethinking Deno.
There were 3 things that drew me to Deno initially:
Ease of install (just run the app from a URL)
Cloud platforms (Deno Deploy w/ Deno KV)
JavaScript (I know the language, and it has a big ecosystem)