albertcardona,
@albertcardona@mathstodon.xyz avatar

"Climbing fibers provide essential instructive signals for associative learning", Silva et al. 2024 from @megancarey 's lab.

https://www.nature.com/articles/s41593-024-01594-7

An interesting and unexpected result: "Moderate ChR2 [channelrhodopsin] expression is associated with subtle reductions in CF [climbing fibre] signaling and abolishes learning to a sensory US [unconditioned stimulus]."

This lead to the "zombie neurons" concept, explained also in the institutional press release: https://www.fchampalimaud.org/news/zombie-neurons-shed-light-how-brain-learns

#neuroscience #cerebellum

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